Lithium Treatment and Thyroid Disorders

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Lithium Treatment and Thyroid Disorders

Lithium was first discovered as a chemical element in 1817. By the mid-1800s, there was great interest in “urate imbalances”, which were thought to explain a variety of diseases, including mania and depression. Around this time, it was discovered that a solution of lithium carbonate could dissolve stones made of urate. The first recorded use of lithium for the treatment of mania, based in part ...

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Lithium Therapy and Thyroid Disorders

Lithium carbonate is used as a first-line treatment for bipolar disorder and is given to approximately 1 in every 200 patients with this psychiatric disease. Lithium, an element in the alkali metal group, has a variety of anti-thyroid effects, primarily goiter formation and hypothyroidism. Rarely, lithium may cause hyperthyroidism secondary to thyroiditis or through possible autoimmune actions....

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Lithium treatment and thyroid abnormalities

BACKGROUND Although the interactions between lithium treatment and thyroid function have long been recognised, their clinical relevance is still controversial. This paper sets out a review of the literature to date, considering that lithium still represents the gold standard among prophylactic treatments of manic-depression several decades after its introduction. METHOD PubMed database was us...

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Lithium Treatment in Affective Disorders

50 manic patients of unipolar and bipolar affective illness were placed on oral lithium 600-1500 mg daily and serum levels in the range of 0.49-1.23 mEq/L. A better response in bipolar disorders than unipolar was observed. Besides, a much better response to lithium therapy is observed in patients with disease of longer duration and a positive history of affective illness in blood relations. The...

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ژورنال

عنوان ژورنال: Journal of Thyroid Disorders & Therapy

سال: 2014

ISSN: 2167-7948

DOI: 10.4172/2167-7948.1000143